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Emerg Infect Dis. 2006 Jul;12(7):1145-8.

Replicon typing of plasmids encoding resistance to newer beta-lactams.

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  • 1Department of Infectious, Parasituc, Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy. alecara@iss.it

Abstract

Polymerase chain reaction-based replicon typing represents a novel method to describe the dissemination and follow the evolution of resistance plasmids. We used this approach to study 26 epidemiologically unrelated Enterobacteriaceae and demonstrate the dominance of incompatibility (Inc) A/C or Inc N-related plasmids carrying some emerging resistance determinants to extended-spectrum cephalosporins and carbapenems.

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