Format

Send to

Choose Destination
See comment in PubMed Commons below
Behav Res Methods. 2006 Feb;38(1):77-87.

Demonstration and evaluation of a method for assessing mediated moderation.

Author information

  • 1Center for Interdisciplinary Substance Abuse Research, Research Triangle Institute, International, 3040 Cornwallis Road, Research Triangle Park, NC 27709, USA. amorganlopez@rti.org

Abstract

Mediated moderation occurs when the interaction between two variables affects a mediator, which then affects a dependent variable. In this article, we describe the mediated moderation model and evaluate it with a statistical simulation using an adaptation of product-of-coefficients methods to assess mediation. We also demonstrate the use of this method with a substantive example from the adolescent tobacco literature. In the simulation, relative bias (RB) in point estimates and standard errors did not exceed problematic levels of +/- 10% although systematic variability in RB was accounted for by parameter size, sample size, and nonzero direct effects. Power to detect mediated moderation effects appears to be severely compromised under one particular combination of conditions: when the component variables that make up the interaction terms are correlated and partial mediated moderation exists. Implications for the estimation of mediated moderation effects in experimental and nonexperimental research are discussed.

PMID:
16817516
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk