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J Physiol. 2006 Sep 1;575(Pt 2):353-9. Epub 2006 Jun 29.

Microarrays and the microscope: balancing throughput with resolution.

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  • 1Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA.

Abstract

The cellular complexity of the brain is a major issue in the planning, execution and interpretation of microarray studies. Recent technical advances allow for high-throughput study of specific cell populations and circuits. Here we review representative examples of currently available methods that allow high resolution and specificity in brain microarray studies, while maintaining the goal of comprehensive, high-throughput analysis.

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