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    Clin Pract Epidemol Ment Health. 2006 Jun 28;2:15.

    A randomized controlled trial of a psychoeducational group program for unipolar depression in adults in Norway (NCT00319540).

    Dalgard OS.

    Norwegian Institute of Public Health, Marcus Thranes gt, 6, P,O, 4404 Oslo, Norway. odd.steffen.dalgard@fhi.no

    BACKGROUND: Coping with Depression Course (CWD) has shown to be effective in the treatment of depression. However, there are very few randomized controlled trials on unipolar depression in adults. AIMS: To test the effect of a modified CWD on unipolar depression in a randomized controlled trial design in adults. METHODS: Participants were recruited through mass media, tested by BDI and clinical interview, and randomized into intervention group (N = 81) and control group (N = 74). The program was mainly conducted by nurses with background in psychiatry and primary health care, and the intervention encompassed 8 weekly sessions of 2 1/2 hours, with 3 booster sessions. RESULTS: By "intention-to-treat" analysis a statistically significant effect on depressive symptoms at follow up at 6 months was found, and the level of symptoms was sustained after 12 months. CONCLUSION: The study shows that the intervention is effective in the treatment of unipolar depression, and suitable for specialized psychiatric services as well as primary health care.

    PMID: 16805912 [PubMed]

    PMCID: PMC1538590

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