Int J Gynaecol Obstet. 1991 May;35(1):83-8.

Associated leukemia and mixed germ cell tumor in a patient with gonadal dysgenesis.

Kaplan SS, Bornstein SG, Christopherson WA, Surti U.

Source

Department of Pathology, University of Pittsburgh School of Medicine, PA.

Abstract

A 16-year-old phenotypic female developed acute myeloblastic leukemia with a fulminant course very shortly after surgery and chemotherapy for a mixed germ cell tumor of the ovary. The karyotype (46, XY, 47, XY + 8) suggested de novo rather than therapy-associated leukemia. The relationship between germ cell tumors and leukemia, their common yolk sac derivation and the role of the Y chromosome are discussed. The idea that XY gonadal dysgenesis may be familial also is discussed.

PMID:: 1680081; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

A 46 XY phenotypic female adolescent with bilateral gonadal tumors consisting of five different components. [Int J Gynecol Pathol. 2008]
A 46 XY phenotypic female adolescent with bilateral gonadal tumors consisting of five different components.
Simon RA, Laughlin TS, Nuccie B, Wang N, Rothberg PG, Wang X. Int J Gynecol Pathol. 2008 Jul; 27(3):407-11.
46 XY pure gonadal dysgenesis with gonadoblastoma and dysgerminoma. [Tunis Med. 2008]
46 XY pure gonadal dysgenesis with gonadoblastoma and dysgerminoma.
Ben Temime R, Chachial A, Attial L, Ghodbanel I, Makhloufl T, Koubaal A, Kourda N, Ben Jilani S, Dammak T, El May A, et al. Tunis Med. 2008 Jul; 86(7):710-3.
True histiocytic malignancy associated with a malignant teratoma in a patient with 46XY gonadal dysgenesis. [Am J Surg Pathol. 1992]
True histiocytic malignancy associated with a malignant teratoma in a patient with 46XY gonadal dysgenesis.
Koo CH, Reifel J, Kogut N, Cove JK, Rappaport H. Am J Surg Pathol. 1992 Feb; 16(2):175-83.
Review Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. [Mod Pathol. 2005]
Review Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.
Ulbright TM. Mod Pathol. 2005 Feb; 18 Suppl 2:S61-79.
Review The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia. A case report and review of the literature. [Cancer Genet Cytogenet. 1995]
Review The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia. A case report and review of the literature.
Woodruff K, Wang N, May W, Adrone E, Denny C, Feig SA. Cancer Genet Cytogenet. 1995 Jan; 79(1):25-31.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

Associated leukemia and mixed germ cell tumor in a patient with gonadal dysgenes...
Associated leukemia and mixed germ cell tumor in a patient with gonadal dysgenesis.
Int J Gynaecol Obstet. 1991 May ;35(1):83-8.

PubMed
Deciphering signaling control by phosphoproteome using mass spectrometry.
Deciphering signaling control by phosphoproteome using mass spectrometry.
Protein Pept Lett. 2006 ;13(5):467-9.

PubMed
Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats.
Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats.
Nutr Cancer. 2006 ;54(1):84-93.

PubMed
Atypical Schild plots with histamine H1 receptor agonists and antagonists in the...
Atypical Schild plots with histamine H1 receptor agonists and antagonists in the rabbit aorta.
Eur J Pharmacol. 1991 May 2 ;197(1):49-56.

PubMed
Selected annotated bibliography.
Selected annotated bibliography.
South Med J. 2006 Jun ;99(6):692-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Associated leukemia and mixed germ cell tumor in a patient with gonadal dysgenesis.

Source

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information