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1: Biol Chem. 2006 Jun;387(6):637-41.Click here to read Links

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins.

Lund University, Clinical Chemistry, Department of Laboratory Medicine, University Hospital MAS, S-205 02 Malmö, Sweden. ake.lundwall@med.lu.se

The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1--the tissue kallikrein--and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

PMID: 16800724 [PubMed - indexed for MEDLINE]