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Int J Clin Pharmacol Ther. 2006 Jun;44(6):247-50.

Plant stanol and sterol esters in prevention of cardiovascular diseases: a review.

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  • 1Department of Medicine, Division of Internal Medicine, University of Helsinki, Helsinki, Finland. tatu.a.miettinen@helsinki.fi

Abstract

Plant sterol and stanol esters have been introduced as an additional dietary means to lower serum total and LDL cholesterol concentration. In short-term studies they lower LDL cholesterol by 10%, and according to a meta-analysis by Malcolm Law the incidence of coronary heart disease is considered to be reduced by over 20% in long-term use of these products. Plant stanol and sterol esters are not identical sterols; they have different metabolic effects and their long-term efficacy seems to be different. The present review deals with the differences of the sterols and discusses what is known of their role in preventing the cardiovascular diseases.

PMID:
16800096
[PubMed - indexed for MEDLINE]
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