Hum Exp Toxicol. 1991 Jul;10(4):289.

Complete heart block after flumazenil.

Source

North Tees General Hospital, Stockton on Tees, Cleveland.

Abstract

Flumazenil is a competitive benzodiazepine antagonist. It is indicated for reversal of excess benzodiazepine sedation under certain circumstances, including the reversal of overdosage effects when it is felt best to avoid ventilation, such as in the very old or the very young. We report a case where the use of flumazenil was associated with complete heart block in an elderly patient.

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Review A risk-benefit assessment of flumazenil in the management of benzodiazepine overdose. [Drug Saf. 1997]
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