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Electromyogr Clin Neurophysiol. 2006 Mar-Apr;46(2):101-4.

Down beat nystagmus in vitamin B 12 deficiency syndrome.

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  • 1Department of Neurology, G.B. Pant Hospital, New Delhi 110 002, India.


A 34 years old male, presenting with progressive proximal weakness, with a neurogenic pattern on needle EMG, and a family history suggestive of an autosomal recessive disorder, was found to have additional features of myeloneuropathy and a down beat nystagmus. A low serum vitamin B12 level was found, and on vitamin B12 supplementation there was a partial clinical as well as electrophysiological recovery.

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