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Bioorg Med Chem Lett. 2006 Sep 1;16(17):4567-70. Epub 2006 Jun 21.

Potent 4-amino-5-azaindole factor VIIa inhibitors.

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  • 1Celera Genomics, South San Francisco, CA 94080, USA. huiyong.hu@yahoo.com

Abstract

The 4-amino-5-azaindole as an amidino-benzimidazole replacement is described. A series of potent and selective analogs were discovered and showed desirable ex vivo efficacy as measured by PT.

PMID:
16793264
[PubMed - indexed for MEDLINE]

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