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AIDS. 2006 Jun 26;20(10):1460-2.

Seroreversion of HIV antibodies in patients with prolonged suppression of viraemia under HAART.

Author information

  • 1Service of Microbiology, Hospital Carlos III, Madrid, Spain.

Abstract

Prolonged virus suppression in chronically HIV-infected patients could hypothetically lead to antibody seroreversion. Eighty-four HIV-positive individuals with undetectable viraemia for longer than 5 years under HAART were examined. Only one individual, who had initiated HAART shortly after primary HIV infection, showed seroreversion. In contrast, the cure of hepatitis C virus (HCV) with interferon in 25 controls led to the loss of HCV antibodies in most cases. This information indirectly reflects that whereas HCV may be eradicable HIV is not.

PMID:
16791025
[PubMed - indexed for MEDLINE]
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