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AIDS. 2006 Jun 26;20(10):1460-2.

Seroreversion of HIV antibodies in patients with prolonged suppression of viraemia under HAART.

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  • 1Service of Microbiology, Hospital Carlos III, Madrid, Spain.


Prolonged virus suppression in chronically HIV-infected patients could hypothetically lead to antibody seroreversion. Eighty-four HIV-positive individuals with undetectable viraemia for longer than 5 years under HAART were examined. Only one individual, who had initiated HAART shortly after primary HIV infection, showed seroreversion. In contrast, the cure of hepatitis C virus (HCV) with interferon in 25 controls led to the loss of HCV antibodies in most cases. This information indirectly reflects that whereas HCV may be eradicable HIV is not.

[PubMed - indexed for MEDLINE]
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