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Pyoderma gangrenosum as initial manifestation of Graves' disease.
Department of Dermatology, Mulhouse General Hospital, and Strasbourg University Hospital, France. cristina_livideanu@yahoo.fr
Pyoderma gangrenosum (PG) is an uncommon ulcerative condition. It is most commonly associated with inflammatory bowel disease, haematological malignancies and autoimmune disease. We report on two patients have developed PG during the initial course of Graves' disease (GD), prior to treatment of this condition. The lesions completely cleared with treatment by colchicine in the first case and with oral ciclosporin in the second case. The report emphasizes that a diagnostics of PG should be considered in patients with GD and skin ulcers.
PMID: 16780496 [PubMed - indexed for MEDLINE]
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Patient Drug Information
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Cyclosporine (Neoral® , Sandimmune® , Gengraf® )
Cyclosporine and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have rec...
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Colchicine Oral
Colchicine relieves swelling and pain caused by attacks of gout or gouty arthritis. It may also be taken regularly to prevent gout or gouty arthritis attacks.