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AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1355-6.

CNS Clostridium perfringens infection: a rare complication of preoperative embolization of meningioma.

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  • 1Department of Radiology, Buddhist Tzu Chi General Hospital, 707 Section 3 Chung Yang Road, Hualien, Taiwan.


Gas gangrene is a severe form of gangrene (tissue death) that usually is caused by Clostridium perfringens. It generally occurs at the site of trauma or a recent surgical wound. We report the case of a 45-year-old woman with sphenoid-ridged meningioma who received preoperative transarterial embolization with polyvinyl alcohol. The patient later developed an intratumoral C perfringens infection and died despite intensive medical care. The case represents an extremely rare complication following transarterial embolization of meningioma.

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