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Clin Perinatol. 2006 Jun;33(2):335-53.

Intrapartum asphyxia and cerebral palsy: is there a link?

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  • 1Department of Pediatrics, Weill Cornell Medical Center, New York, NY 10021, USA.


Perinatal hypoxic-ischemic cerebral injury, secondary to interruption of placental blood flow that results in cerebral palsy (CP), is a rare event. The ability to link an intrapartum event to subsequent CP should include a history of a sentinel event during labor, followed by the delivery of a depressed acidemic infant, and the subsequent evolution of neonatal encephalopathy, systemic organ injury, and acute neuroimaging abnormalities.

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