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Brief Bioinform. 2006 Mar;7(1):86-112.

Machine learning in bioinformatics.

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  • 1Intelligent Systems Group, Department of Computer Science and Artificial Intelligence, University of the Basque Country, Paseo Manuel de Lardizabal, 1, 20018 San Sebastian, Spain. pedro.larranaga@ehu.es


This article reviews machine learning methods for bioinformatics. It presents modelling methods, such as supervised classification, clustering and probabilistic graphical models for knowledge discovery, as well as deterministic and stochastic heuristics for optimization. Applications in genomics, proteomics, systems biology, evolution and text mining are also shown.

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