Gen Pharmacol. 1991;22(1):33-41.

Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--I. Agonists.

Source

School of Biological Sciences, University College of Swansea, U.K.

Abstract

1. The present experiment examined, using a battery of tests, the effects of in utero exposure to the benzodiazepine agonists chlordiazepoxide and midazolam upon the early development and adult behaviour of offspring of Swiss mice. 2. Early development was generally retarded as a result of treatment. 3. Effects on adult social behaviour examined using the resident-intruder paradigm by determining the time spent in broad behavioural categories, showed marginal effects due to chlordiazepoxide and more striking actions due to midazolam treatments. Generally the treatments produced changes suggestive of an increase and a decrease in anxiety in males and females respectively.

PMID:: 1675618; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Comparative Study

MeSH Terms

Substances

LinkOut - more resources

Medical

Health Problems in Pregnancy - MedlinePlus Health Information

Molecular Biology Databases

Supplemental Content

Save items

Related citations in PubMed

Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--III. Inverse agonists. [Gen Pharmacol. 1991]
Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--III. Inverse agonists.
Pankaj V, Brain PF. Gen Pharmacol. 1991; 22(1):53-60.
Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--II. Antagonists. [Gen Pharmacol. 1991]
Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--II. Antagonists.
Pankaj V, Brain PF. Gen Pharmacol. 1991; 22(1):43-51.
Effects of exposure of pregnant mice to chlordiazepoxide (CDP) on the development and ultrasound production of their offspring. [Gen Pharmacol. 1992]
Effects of exposure of pregnant mice to chlordiazepoxide (CDP) on the development and ultrasound production of their offspring.
Kurishingal H, Palanza P, Brain PF. Gen Pharmacol. 1992 Jan; 23(1):49-53.
Review The effects of benzodiazepine use during pregnancy and lactation. [Reprod Toxicol. 1994]
Review The effects of benzodiazepine use during pregnancy and lactation.
McElhatton PR. Reprod Toxicol. 1994 Nov-Dec; 8(6):461-75.
Review Effect of psychotropic drugs administered to pregnant rats on the behaviour of the offspring. [Neuropharmacology. 1981]
Review Effect of psychotropic drugs administered to pregnant rats on the behaviour of the offspring.
Leonard BE. Neuropharmacology. 1981 Dec; 20(12B):1237-42.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Effects of prenatal exposure to benzodiazepine-related drugs on early developmen...
Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--I. Agonists.
Gen Pharmacol. 1991 ;22(1):33-41.

PubMed
[Prevention of influenza in infants].
[Prevention of influenza in infants].
Vopr Virusol. 2006 Mar-Apr ;51(2):4-10.

PubMed
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites i...
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes.
Eur J Pharmacol. 1991 Jan 25 ;193(1):21-7.

PubMed
[Analysis of nucleotide diversity at the cytochrome b and cytochrome oxidase 1 g...
[Analysis of nucleotide diversity at the cytochrome b and cytochrome oxidase 1 genes at the population, species, and genus levels].
Genetika. 2006 Apr ;42(4):437-61.

PubMed
Atypical presentation of HIV in a pregnant patient.
Atypical presentation of HIV in a pregnant patient.
Ulster Med J. 2006 May ;75(2):160-1.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: