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Magn Reson Med. 2006 Jul;56(1):167-76.

Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system.

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  • 1Applied Science Laboratory, GE Healthcare Technologies, Boston, Massachusetts, USA. niendorf@rad.rwth-aachen.de

Abstract

Coronary MR angiography (CMRA) is generally confined to the acquisition of multiple targeted slabs with coverage dictated by the competing constraints of signal-to-noise ratio (SNR), physiological motion, and scan time. This work addresses these obstacles by demonstrating the technical feasibility of using a 32-channel coil array and receiver system for highly accelerated volumetric breath-hold CMRA. The use of the 32-element array in unaccelerated CMRA studies provided a baseline SNR increase of as much as 40% over conventional cardiac-optimized phased array coils, which resulted in substantially enhanced image quality and improved delineation of the coronary arteries. Modest accelerations were used to reduce breath-hold durations for tailored coverage of the coronary arteries using targeted multi-oblique slabs to as little as 10 s. Finally, high net accelerations were combined with the SNR advantages of a 3D steady-state free precession (SSFP) technique to achieve previously unattainable comprehensive volumetric coverage of the coronary arteries in a single breath-hold. The merits and limitations of this simplified volumetric imaging approach are discussed and its implications for coronary MRA are considered.

Copyright (c) 2006 Wiley-Liss, Inc.

PMID:
16755538
[PubMed - indexed for MEDLINE]
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