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Annu Rev Microbiol. 2006;60:397-423.

Surface proteins of gram-positive bacteria and how they get there.

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  • 1Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.


Surface proteins are critical in determining the identifying characteristics of individual bacteria and their interaction with the environment. Because the structure of the cell surface is the major characteristic that distinguishes gram-positive from gram-negative bacteria, the processes used to transport and attach these proteins show significant differences between these bacterial classes. This review is intended to highlight these differences and to focus attention on areas that are ripe for further investigation.

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