Format

Send to:

Choose Destination
See comment in PubMed Commons below
PLoS Pathog. 2006 May;2(5):e42.

Crossing the line: selection and evolution of virulence traits.

Author information

  • 1Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

Abstract

The evolution of pathogens presents a paradox. Pathogenic species are often absolutely dependent on their host species for their propagation through evolutionary time, yet the pathogenic lifestyle requires that the host be damaged during this dependence. It is clear that pathogenic strategies are successful in evolutionary terms because a diverse array of pathogens exists in nature. Pathogens also evolve using a broad range of molecular mechanisms to acquire and modulate existing virulence traits in order to achieve this success. Detailing the benefit of enhanced selection derived through virulence and understanding the mechanisms through which virulence evolves are important to understanding the natural world and both have implications for human health.

PMID:
16733541
[PubMed - indexed for MEDLINE]
PMCID:
PMC1464392
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Public Library of Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk