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Bioinformatics. 2006 Aug 1;22(15):1919-20. Epub 2006 May 26.

ACE-it: a tool for genome-wide integration of gene dosage and RNA expression data.

Author information

  • 1Department of Mathematics, Vrije Universiteit De Boelelaan 1081, 1081 HV, Amsterdam, The Netherlands.

Abstract

SUMMARY:

We describe a tool, called ACE-it (Array CGH Expression integration tool). ACE-it links the chromosomal position of the gene dosage measured by array CGH to the genes measured by the expression array. ACE-it uses this link to statistically test whether gene dosage affects RNA expression.

AVAILABILITY:

ACE-it is freely available at http://ibivu.cs.vu.nl/programs/acewww/.

PMID:
16731696
[PubMed - indexed for MEDLINE]
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