Candida meningitis in a suspected immunosuppressive patient--a case report

West Afr J Med. 2006 Jan-Mar;25(1):79-81. doi: 10.4314/wajm.v25i1.28251.

Abstract

Meningitis due to fungal agents represents an AIDS-defining event and occurs typically with very low CD4+ lymphocyte count. Candida meningitis is still a rare clinical condition, although it is becoming frequently reported in the background of immune suppressive states such as: drug addicts, cancer patients, organ transplant recipients and HIV/AIDS patients. In this report we highlight a case of candida meningitis, in a 25- year old female patient. She presented with vulva swelling, vaginal discharge and fever, with rapid progression to tonic-clonic convulsions and loss of consciousness. She fully recovered after treatment with fluconazole.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis
  • AIDS-Related Opportunistic Infections / immunology
  • AIDS-Related Opportunistic Infections / microbiology
  • Adult
  • Antifungal Agents / therapeutic use
  • Candida albicans / isolation & purification
  • Candidiasis, Vulvovaginal / diagnosis*
  • Candidiasis, Vulvovaginal / immunology*
  • Candidiasis, Vulvovaginal / microbiology
  • Female
  • Fluconazole / therapeutic use
  • Humans
  • Immunocompromised Host*
  • Meningitis, Fungal / diagnosis*
  • Meningitis, Fungal / immunology*
  • Meningitis, Fungal / microbiology
  • Treatment Outcome
  • Vagina / microbiology

Substances

  • Antifungal Agents
  • Fluconazole