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    Microbes Infect. 2006 Jun;8(7):1915-22. Epub 2006 Mar 27.

    The genetics of Salmonella genomic island 1.

    Source

    National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada. michael_mulvey@phac-aspc.gc.ca

    Abstract

    Multidrug-resistant Salmonella enterica serovar Typhimurium phage type DT104, resistant to ampicillin, chloramphenicol/florfenicol, streptomycin, sulfonamides, and tetracycline, has disseminated worldwide. The resistance genes reside on the 43-kb Salmonella genomic island 1 (SGI1), which is transferable. Drug-resistant variants of SGI1 have been identified in numerous serotypes. Strains harboring SGI1 may be more virulent and have a tendency to rapidly disseminate.

    PMID:
    16713724
    [PubMed - indexed for MEDLINE]

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