Class 1 integrons in resistant Escherichia coli and Klebsiella spp., US hospitals

Aarati N Rao; Miriam Barlow; Leigh Ann Clark; John R Boring 3rd; Fred C Tenover; John E McGowan Jr

doi:10.3201/eid1206.051596

Class 1 integrons in resistant Escherichia coli and Klebsiella spp., US hospitals

Emerg Infect Dis. 2006 Jun;12(6):1011-4. doi: 10.3201/eid1206.051596.

Authors

Aarati N Rao¹, Miriam Barlow, Leigh Ann Clark, John R Boring 3rd, Fred C Tenover, John E McGowan Jr

Affiliation

¹ Emory University, Atlanta, Georgia 30322, USA.

Abstract

We examined Escherichia coli and Klebsiella spp. from US hospitals for class 1 integrons. Of 320 isolates, 181 (57%) were positive; association of integrons with resistance varied by drug and organism. Thus, determining integron epidemiology will improve understanding of how antibacterial resistance determinants spread in the United States.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA, Bacterial / chemistry
DNA, Bacterial / genetics
Drug Resistance, Bacterial / genetics
Electrophoresis, Agar Gel
Escherichia coli / drug effects
Escherichia coli / genetics*
Escherichia coli / isolation & purification
Escherichia coli Infections / microbiology*
Hospitals
Humans
Integrons / genetics*
Klebsiella / drug effects
Klebsiella / genetics*
Klebsiella / isolation & purification
Klebsiella Infections / microbiology*
Logistic Models
Microbial Sensitivity Tests
Multivariate Analysis
Polymerase Chain Reaction
United States / epidemiology

Substances

DNA, Bacterial