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Hepatobiliary Pancreat Dis Int. 2006 May;5(2):305-7.

Breast carcinoma with metastasis to the gallbladder: an unusual case report with a short review of literature.

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  • 1Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector- 5, Delhi-110085, India.


Gallbladder metastases are very rare and usually arise from malignant melanoma, renal cell carcinoma and cervical carcinoma. Breast carcinoma metastatic to the gallbladder is extremely rare and only 4 cases have been reported in the English literature. We hereby report a 54-year-old lady who was diagnosed as having breast carcinoma and underwent modified radical mastectomy. One month after the operation, she developed acute abdominal pain and underwent cholecystectomy after clinical investigation. Histopathological examination revealed metastasis to the gallbladder. Being considered a patient with metastatic breast carcinoma she was subjected to taxane and anthracycline-based palliative chemotherapy. Later she had CNS involvement and died of the progressive disease soon after few months.

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