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Lancet. 2006 May 13;367(9522):1605-17.

Cushing's syndrome.

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  • 1Division of Clinical Sciences, University of Sheffield, Northern General Hospital, Sheffield, UK. j.newellprice@sheffield.ac.uk

Abstract

Cushing's syndrome results from lengthy and inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains a challenge to diagnose and manage. Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches. We provide diagnostic algorithms and recommendations for management.

PMID:
16698415
[PubMed - indexed for MEDLINE]
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