-
Histone H4 lysine 16 acetylation breaks the genome's silence.
Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Acetylation at histone H4 lysine 16 is involved in many cellular processes in organisms as diverse as yeast and humans. A recent biochemical study pinpoints this particular acetylation mark as a switch for changing chromatin from a repressive to a transcriptionally active state.
PMID: 16689998 [PubMed - indexed for MEDLINE]
PMCID: PMC1779524
-
Cited by 2 PubMed Central articles
-
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, et al.
Mol Cell Biol. 2008 Jan; 28(1):397-409. Epub 2007 Oct 29.
[Mol Cell Biol. 2008]
-
ChIP on SNP-chip for genome-wide analysis of human histone H4 hyperacetylation.
McCann JA, Muro EM, Palmer C, Palidwor G, Porter CJ, Andrade-Navarro MA, Rudnicki MA.
BMC Genomics. 2007 Sep 14; 8:322. Epub 2007 Sep 14.
[BMC Genomics. 2007]