Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Skin Pharmacol Physiol. 2006;19(2):71-7. Epub 2006 May 9.

Tight junction proteins in the skin.

Author information

  • 1Department of Dermatology and Venerology, University Hospital Hamburg-Eppendorf, Germany. brandner@uke.uni-hamburg.de

Abstract

It has long been accepted that tight junctions (TJ) are crucial for the formation and maintenance of the paracellular barrier and for cell polarity in simple epithelia and endothelia. Moreover, it is long known that they play a role in barrier function of amphibian skin. However, only in recent years were TJ and TJ proteins identified in the epidermis of men and mice. Their involvement in the barrier function of mammalian skin has been shown. This review summarizes our current knowledge about TJ and TJ proteins in mammalian skin.

Copyright 2006 S. Karger AG, Basel.

PMID:
16685145
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland
    Loading ...
    Write to the Help Desk