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    Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt 5):427-31. Epub 2006 Apr 12.

    Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.

    Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA.

    Structural Genomics of Pathogenic Protozoa (SGPP) Consortium, USA.

    The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family.

    PMID: 16682767 [PubMed - indexed for MEDLINE]

    PMCID: 2219984

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