Send to:

Choose Destination
See comment in PubMed Commons below
Trends Genet. 1991 Nov-Dec;7(11-12):393-8.

Signal transduction in yeast mating: receptors, transcription factors, and the kinase connection.

Author information

  • 1Institute of Molecular Biology, University of Oregon, Eugene 97403.


In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. binding of pheromone to G-protein-coupled receptors activates a cascade of serine/threonine protein kinases that ultimately phosphorylate and increase the activity of an identified transcription factor.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk