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Neurol India. 2006 Mar;54(1):75-7.

Neuropsychiatric manifestations systemic lupus erythematosus: a study from South India.

Author information

  • 1Department of Neurology, Medical College Hospital, Trivandrum, Kerala, India. robert_mathew@hotmail.com

Abstract

CONTEXT:

Neuropsychiatric systemic lupus erythematosus (NPSLE) has varied manifestations.

AIMS:

To study the pattern of neuropsychiatric (NP) involvement in systemic lupus erythematosus (SLE).

SETTINGS AND DESIGN:

Hospital based cross sectional and retrospective study.

PATIENTS AND METHODS:

Patients admitted with a diagnosis of SLE, during a period of 16 months, were evaluated and any NP syndrome present classified as per the American College of Rheumatology (ACR) nomenclature.

STATISTICAL ANALYSIS:

SPSS software Version 10 was used for descriptive analysis and correlative study.

RESULTS:

Out of 50 patients with SLE, all the patients with NPSLE [39 (78%)] were females, mean age 25.66 years (range: 11-44). The commonest manifestation was headache [20 (55.6%)]. Seizures were seen in 8 (20.51%) and psychosis in 6 (16.2%). Fine distal tremor was seen in 8 (20.51%) of patients.

CONCLUSIONS:

Headache is a frequent NP syndrome. Fine distal tremor is a syndrome not included in ACR classification but seen is 20% of our patients with NPSLE.

PMID:
16679649
[PubMed - indexed for MEDLINE]
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