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Genome Biol. 2006;7(4):214. Epub 2006 Apr 27.

Getting to synaptic complexes through systems biology.

Author information

  • 1Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA.

Abstract

Large numbers of synaptic components have been identified, but the effect so far on our understanding of synaptic function is limited. Now, network maps and annotated functions of individual components have been used in a systems biology approach to analyzing the function of NMDA receptor complexes at synapses, identifying biologically relevant modular networks within the complex.

PMID:
16677427
[PubMed - indexed for MEDLINE]
PMCID:
PMC1558000
Free PMC Article
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