Glycobiology. 2006 Aug;16(8):113R-136R. Epub 2006 May 4.

Glycopeptides as versatile tools for glycobiology.

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Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA, USA.

Abstract

This review describes the recent advances in the field of glycopeptide and small glycoprotein synthesis. The strategies covered include chemical and chemoenzymatic synthesis, native chemical ligation (NCL), and expressed chemical ligation. The importance of glycopeptide synthesis is exemplified by giving the reader an overview of how versatile and important these well-defined glycopeptides are as tools in glycobiology.

PMID:: 16675547; [PubMed - indexed for MEDLINE]

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R01 CA 88986/CA/NCI NIH HHS/United States

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