Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Microbiol. 2006 May;44(5):1899-902.

Development and evaluation of a loop-mediated isothermal amplification method for rapid diagnosis of Bordetella pertussis infection.

Author information

  • 1Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, Musashimurayma-city, Tokyo 208-0011, Japan. kamachi@nih.go.jp

Abstract

We developed a loop-mediated isothermal amplification (LAMP) method to detect Bordetella pertussis infection. This LAMP assay detected B. pertussis with high sensitivity, but not other Bordetella species. Among nasopharyngeal swab samples from subjects with suspected pertussis, LAMP results showed a high level of agreement with results of conventional PCR. This method is a rapid, sensitive, and specific method for diagnosis of B. pertussis infection even in clinical laboratories with no specific equipment.

PMID:
16672435
[PubMed - indexed for MEDLINE]
PMCID:
PMC1479160
Free PMC Article

Images from this publication.See all images (1)Free text

FIG. 1.
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk