Trends Biochem Sci. 1991 Dec;16(12):478-81.

Nuclear targeting sequences--a consensus?

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Wellcome Trust/Cancer Research Campaign Institute of Cancer and Development Biology, Cambridge.

Abstract

Nuclear targeting sequences are essential for the transport of proteins into the nucleus. The seven-amino-acid nuclear targeting sequence of the SV40 large T antigen has been regarded as the model; however, many nuclear targeting sequences appear to be more complex. We suggest in this review that, despite this diversity, a consensus bipartite motif can be identified.

Comment in

A bipartite nuclear targeting motif in protein kinase C? [Trends Biochem Sci. 1992]
A bipartite nuclear targeting motif in protein kinase C?Malviya AN, Block C. Trends Biochem Sci. 1992 May; 17(5):176.
Nuclear targeting sequences. [Trends Biochem Sci. 1992]
Nuclear targeting sequences.Friedberg EC. Trends Biochem Sci. 1992 Sep; 17(9):347.

PMID:: 1664152; [PubMed - indexed for MEDLINE]

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