Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:92-8.

The PediaFlow pediatric ventricular assist device.

Source

Section of Pediatric Cardiothoracic Surgery of the Heart Lung and Esophageal Institute, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

Abstract

The very limited options available to treat ventricular failure in patients with congenital and acquired heart diseases have motivated the development of a pediatric ventricular assist device (VAD). Our effort involves a consortium consisting of the University of Pittsburgh, Carnegie Mellon University, Children's Hospital of Pittsburgh, World Heart Corporation, and LaunchPoint Technologies, LLC. The overall aim of our program is to develop a highly reliable, biocompatible VAD for chronic support (6 months) of the unique and high-risk population of children between 3 kg and 15 kg (patients from birth to 2 years of age). The innovative pediatric VAD we are developing (PediaFlow) is based on a miniature mixed-flow turbodynamic pump featuring magnetic levitation, with the design goal being to assure minimal blood trauma and risk of thrombosis. This article discusses the limitations of current pediatric cardiac assist treatment options and the work to date by our consortium toward the development of a pediatric VAD.

PMID:: 16638553; [PubMed - indexed for MEDLINE]

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Biocompatible Materials

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N01-HV-48192/HV/NHLBI NIH HHS/United States

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Cited by 2 PubMed Central articles

Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device. [Artif Organs. 2011]
Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device.
Johnson CA Jr, Vandenberghe S, Daly AR, Woolley JR, Snyder ST, Verkaik JE, Ye SH, Borovetz HS, Antaki JF, Wearden PD, et al. Artif Organs. 2011 Jan; 35(1):9-21.
Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support. [ASAIO J. 2007]
Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support.
Dasse KA, Gellman B, Kameneva MV, Woolley JR, Johnson CA, Gempp T, Marks JD, Kent S, Koert A, Richardson JS, et al. ASAIO J. 2007 Nov-Dec; 53(6):771-7.

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The PediaFlow pediatric ventricular assist device.
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Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006 :92-8.

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