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Eur J Obstet Gynecol Reprod Biol. 1991 Dec 13;42(3):237-9.

Treatment of a patient with vulvar vestibulitis by intramuscular interferon beta; a case report.

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  • 1Department of Obstetrics and Gynecology, Lady Davis Carmel Hospital, Haifa, Israel.


A patient with severe dyspareunia caused by vulvar vestibulitis, associated with human papillomavirus infection, was treated by intramuscular interferon beta. The treatment was well tolerated and no side effects were reported. A complete resolution of the vestibulitis was noticed 2 months later. No recurrence was noted during a year of follow-up.

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