Semin Reprod Med. 2006 Apr;24(2):71-7.

Androgen physiology.

Source

Women's Health Program, Department of Medicine, Monash Medical School, Alfred Hospital, Prahran, Victoria, Australia. Sonia.Davison@med.monash.edu.au

Abstract

Androgen receptors are present in numerous tissues throughout the female body, and knowledge of the specific actions of androgens at different sites is increasing, along with the understanding of their contribution to various pathophysiological states. This article reviews the physiology of androgens (testosterone and dihydrotestosterone) and immediate androgen precursors (dehydroepiandrosterone [DHEA], dehydroepiandrosterone sulfate [DHEAS], and androstenedione), with specific reference to the androgen receptor, production and metabolism of C- (19) steroids, circulating androgen concentrations, and androgen actions. In addition, the evidence for physiological modulation of androgens including circadian variation, cyclical variation, age, and natural menopause is reviewed.

PMID:: 16633980; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Supplemental Content

Related citations

Review Androgen production in women. [Fertil Steril. 2002]
Review Androgen production in women.
Burger HG. Fertil Steril. 2002 Apr; 77 Suppl 4:S3-5.
Review Androgen metabolism and the menopause. [Semin Reprod Endocrinol. 1998]
Review Androgen metabolism and the menopause.
Longcope C. Semin Reprod Endocrinol. 1998; 16(2):111-5.
Anabolic steroids, testosterone-precursors and virilizing androgens induce distinct activation profiles of androgen responsive promoter constructs. [J Steroid Biochem Mol Biol. 2002]
Anabolic steroids, testosterone-precursors and virilizing androgens induce distinct activation profiles of androgen responsive promoter constructs.
Holterhus PM, Piefke S, Hiort O. J Steroid Biochem Mol Biol. 2002 Nov; 82(4-5):269-75.
The endogenous concentration and subcellular distribution of androgens in normal human premenopausal endometrium, myometrium and vagina. [Gynecol Endocrinol. 1988]
The endogenous concentration and subcellular distribution of androgens in normal human premenopausal endometrium, myometrium and vagina.
Vermeulen-Meiners C, Poortman J, Nabuurs M, Thijssen JH. Gynecol Endocrinol. 1988 Jun; 2(2):121-30.
Review [Mechanism of action and peripheral metabolism of androgens in women]. [Rev Fr Gynecol Obstet. 1989]
Review [Mechanism of action and peripheral metabolism of androgens in women].
Pugeat M. Rev Fr Gynecol Obstet. 1989 Jun; 84(6):475-8.

See reviews... See all...

Cited by 3 PubMed Central articles

Review Androgen therapy and atherosclerotic cardiovascular disease. [Vasc Health Risk Manag. 2008]
Review Androgen therapy and atherosclerotic cardiovascular disease.
McGrath KC, McRobb LS, Heather AK. Vasc Health Risk Manag. 2008; 4(1):11-21.
The functional anatomy of semantic retrieval is influenced by gender, menstrual cycle, and sex hormones. [J Neural Transm. 2008]
The functional anatomy of semantic retrieval is influenced by gender, menstrual cycle, and sex hormones.
Konrad C, Engelien A, Schöning S, Zwitserlood P, Jansen A, Pletziger E, Beizai P, Kersting A, Ohrmann P, Luders E, et al. J Neural Transm. 2008 Sep; 115(9):1327-37. Epub 2008 Jun 12.
Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides. [BMC Complement Altern Med. 2007]
Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides.
Ong VY, Tan BK. BMC Complement Altern Med. 2007 Jan 29; 7:3. Epub 2007 Jan 29.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
BioSystems
Pathways and biological systems (BioSystems) that cite the current articles. Citations are from the BioSystems source databases (KEGG and BioCyc).
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Androgen physiology.
Androgen physiology.
Semin Reprod Med. 2006 Apr ;24(2):71-7.

PubMed
Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, d...
Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity.
J Lipid Res. 2009 Feb ;50(2):183-92. Epub 2008 Sep 11 .

PubMed
Textured surface breast implants in the prevention of capsular contracture among...
Textured surface breast implants in the prevention of capsular contracture among breast augmentation patients: a meta-analysis of randomized controlled trials.
Plast Reconstr Surg. 2006 Jun ;117(7):2182-90.

PubMed
B-cell activation by membrane-bound antigens is facilitated by the interaction o...
B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1.
EMBO J. 2006 Feb 22 ;25(4):889-99. Epub 2006 Feb 2 .

PubMed
Bleeding esophageal varices. How to treat this dreaded complication of portal hy...
Bleeding esophageal varices. How to treat this dreaded complication of portal hypertension.
Postgrad Med. 2001 Feb ;109(2):75-6, 81-6, 89.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Androgen physiology.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Related citations

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information