Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Infect Dis. 2006 May 15;193(10):1437-40. Epub 2006 Apr 4.

Virological response to highly active antiretroviral therapy is unaffected by antituberculosis therapy.

Author information

  • 1Department of HIV Medicine, Royal Free Hospital, and Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom. r.breen@medsch.ucl.ac.uk

Abstract

We compared 156 human immunodeficiency virus (HIV)-infected patients who had tuberculosis with control populations of similar size. Of 111 patients with HIV infection and tuberculosis who received highly active antiretroviral therapy (HAART) and therapy for tuberculosis concurrently, 92 (83%) achieved or maintained virus loads of <50 copies/mL, and 99 (89%) achieved or maintained a >or=2 log10 reduction in virus load after 6 months. Virological response and changes in CD4 cell count were equivalent to those in 111 matched HIV-infected subjects without tuberculosis starting HAART. Tuberculosis recurrence rates were similar to those found in an HIV-uninfected population of 156 subjects (3% and 1%, respectively). Treatment for HIV and tuberculosis does not compromise outcomes for either disease.

PMID:
16619192
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk