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Structure. 2006 Apr;14(4):631-2.

ESCRT complexes assembled and GLUEd.

Abstract

The ESCRT-I, -II, and -III complexes act sequentially to sort monoubiquitinated transmembrane proteins into multivesicular bodies for targeted degradation in the lysosome. Two papers published in a recent issue of Cell provide insights into the structural organization and functional interactions of the ESCRT-I complex and ESCRT-II GLUE domain.

PMID:
16615903
[PubMed - indexed for MEDLINE]
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