Bioinformatics. 2006 Jun 15;22(12):1532-3. Epub 2006 Apr 13.

FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster.

Source

MRC Laboratory of Molecular Biology Cambridge CB2 2QH, UK. boris@mrc-lmb.cam.ac.uk

Abstract

SUMMARY: We present a manually annotated catalogue of site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. These were identified from a list of candidate proteins with transcription-related Gene Ontology (Go) annotation as well as structural DNA-binding domain assignments. For all 1052 candidate proteins, a defined set of rules was applied to classify information from the literature and computational data sources with respect to both DNA-binding and transcriptional regulatory properties. We propose a set of 753 TFs in the fruit fly, of which 23 are confident novel predictions of this function for previously uncharacterized proteins.

PMID:: 16613907; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Molecular Biology Databases

FlyBase

Supplemental Content

Related citations

FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database. [Nucleic Acids Res. 2010]
FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database.
Pfreundt U, James DP, Tweedie S, Wilson D, Teichmann SA, Adryan B. Nucleic Acids Res. 2010 Jan; 38(Database issue):D443-7. Epub 2009 Nov 1.
A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. [J Biol Chem. 2003]
A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.
Sato S, Tomomori-Sato C, Banks CA, Parmely TJ, Sorokina I, Brower CS, Conaway RC, Conaway JW. J Biol Chem. 2003 Dec 12; 278(50):49671-4. Epub 2003 Oct 22.
Functional trends in structural classes of the DNA binding domains of regulatory transcription factors. [Pac Symp Biocomput. 2008]
Functional trends in structural classes of the DNA binding domains of regulatory transcription factors.
McCord RP, Bulyk ML. Pac Symp Biocomput. 2008; :441-52.
Review Drosophila Myc. [Adv Cancer Res. 2009]
Review Drosophila Myc.
Gallant P. Adv Cancer Res. 2009; 103:111-44.
Review Descartes' fly: the geometry of genomic annotation. [Funct Integr Genomics. 2001]
Review Descartes' fly: the geometry of genomic annotation.
Kim J. Funct Integr Genomics. 2001 Mar; 1(4):241-9.

See reviews... See all...

Cited by 20 PubMed Central articles

modMine: flexible access to modENCODE data. [Nucleic Acids Res. 2012]
modMine: flexible access to modENCODE data.
Contrino S, Smith RN, Butano D, Carr A, Hu F, Lyne R, Rutherford K, Kalderimis A, Sullivan J, Carbon S, et al. Nucleic Acids Res. 2012 Jan; 40(Database issue):D1082-8. Epub 2011 Nov 12.
AnimalTFDB: a comprehensive animal transcription factor database. [Nucleic Acids Res. 2012]
AnimalTFDB: a comprehensive animal transcription factor database.
Zhang HM, Chen H, Liu W, Liu H, Gong J, Wang H, Guo AY. Nucleic Acids Res. 2012 Jan; 40(Database issue):D144-9. Epub 2011 Nov 12.
Behavior-specific changes in transcriptional modules lead to distinct and predictable neurogenomic states. [Proc Natl Acad Sci U S A. 2011]
Behavior-specific changes in transcriptional modules lead to distinct and predictable neurogenomic states.
Chandrasekaran S, Ament SA, Eddy JA, Rodriguez-Zas SL, Schatz BR, Price ND, Robinson GE. Proc Natl Acad Sci U S A. 2011 Nov 1; 108(44):18020-5. Epub 2011 Sep 29.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

FlyTF: a systematic review of site-specific transcription factors in the fruit f...
FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster.
Bioinformatics. 2006 Jun 15 ;22(12):1532-3. Epub 2006 Apr 13 .

PubMed
Antioxidative properties of brown algae polyphenolics and their perspectives as ...
Antioxidative properties of brown algae polyphenolics and their perspectives as chemopreventive agents against vascular risk factors.
Arch Pharm Res. 2003 Apr ;26(4):286-93.

PubMed
Cross-cultural evaluation of the modified Parkinson Psychosis Rating Scale acros...
Cross-cultural evaluation of the modified Parkinson Psychosis Rating Scale across disease stages.
Mov Disord. 2010 Jul 30 ;25(10):1391-8.

PubMed
In-hospital stroke: a multi-centre prospective registry.
In-hospital stroke: a multi-centre prospective registry.
Eur J Neurol. 2011 Jan ;18(1):170-6. doi: 10.1111/j.1468-1331.2010.03105.x.

PubMed
The clinical significance of Candida colonization of respiratory tract secretion...
The clinical significance of Candida colonization of respiratory tract secretions in critically ill patients.
J Crit Care. 2008 Mar ;23(1):11-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: