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    Biochem Biophys Res Commun. 1991 Nov 27;181(1):184-90.

    Cloning and chromosomal localization of a human endothelin ETA receptor.

    Cyr C, Huebner K, Druck T, Kris R.

    Source

    Department of Pharmacology, New York University Medical Center, New York 10016.

    Abstract

    A cDNA clone encoding a human endothelin receptor was isolated from a placenta cDNA library. The deduced amino acid sequence of the clone is 94% identical to the bovine endothelin ETA receptor and represents the human homologue. The human endothelin ETA receptor gene was localized to chromosome 4 by analysis of its segregation pattern in rodent-human hybrids.

    PMID:
    1659806
    [PubMed - indexed for MEDLINE]

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