Seroprevalence and molecular epidemiology of human T-Cell leukemia virus type 1 (HTLV-1) and HTLV-2 in blood donors from Dakar, Senegal

J Clin Microbiol. 2006 Apr;44(4):1550-4. doi: 10.1128/JCM.44.4.1550-1554.2006.

Abstract

In 2002, human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 seroprevalence was 0.16% (8/4,900) in blood donors from Dakar, Senegal. Most of the positive donors originated from the country's southern region. Seven donors were infected by HTLV-1 (of cosmopolitan subtype), and one was infected by HTLV-2. These data highlight the problem of transfusion safety in this area where HTLV-1-associated lymphoproliferative and neurological diseases are endemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Donors
  • HTLV-I Antibodies / analysis
  • HTLV-I Antigens / analysis
  • HTLV-I Antigens / immunology
  • HTLV-I Infections / epidemiology*
  • HTLV-I Infections / immunology
  • HTLV-I Infections / virology
  • HTLV-II Antibodies / analysis
  • HTLV-II Antigens / analysis
  • HTLV-II Antigens / immunology
  • HTLV-II Infections / epidemiology*
  • HTLV-II Infections / immunology
  • HTLV-II Infections / virology
  • Human T-lymphotropic virus 1 / genetics*
  • Human T-lymphotropic virus 1 / isolation & purification
  • Human T-lymphotropic virus 2 / genetics*
  • Human T-lymphotropic virus 2 / isolation & purification
  • Humans
  • Molecular Epidemiology*
  • Molecular Sequence Data
  • Phylogeny
  • Prospective Studies
  • Senegal / epidemiology
  • Seroepidemiologic Studies*

Substances

  • HTLV-I Antibodies
  • HTLV-I Antigens
  • HTLV-II Antibodies
  • HTLV-II Antigens

Associated data

  • GENBANK/DQ235698
  • GENBANK/DQ235699
  • GENBANK/DQ235700
  • GENBANK/DQ235701
  • GENBANK/DQ235702
  • GENBANK/DQ235703
  • GENBANK/DQ235704
  • GENBANK/DQ235705
  • GENBANK/DQ235706