Format

Send to

Choose Destination
See comment in PubMed Commons below
Comp Biochem Physiol A Mol Integr Physiol. 2007 Apr;146(4):621-31. Epub 2006 Mar 2.

Oxidative stress and its effects during dehydration.

Author information

  • 1Departamento de Bioquímica, Instituto de Química, UFRJ, 21949-900, Rio de Janeiro, RJ, Brazil.

Abstract

Water is usually thought to be required for the living state, but several organisms are capable of surviving complete dehydration (anhydrobiotes). Elucidation of the mechanisms of tolerance against dehydration may lead to development of new methods for preserving biological materials that do not normally support drying, which is of enormous practical importance in industry, in clinical medicine as well as in agriculture. One of the molecular mechanisms of damage leading to death in desiccation-sensitive cells upon drying is free-radical attack to phospholipids, DNA and proteins. This review aims to summarize the strategies used by anhydrobiotes to cope with the danger of oxygen toxicity and to present our recent results about the importance of some antioxidant defense systems in the dehydration tolerance of Saccharomyces cerevisiae, a usual model in the study of stress response.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk