Clin Orthop Relat Res. 1991 Nov;(272):255-8.

Histologic analysis of a retrieved hydroxyapatite-coated femoral prosthesis.

Søballe K, Gotfredsen K, Brockstedt-Rasmussen H, Nielsen PT, Rechnagel K.

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Department of Orthopaedic Surgery, Hilleroed Hospital, Denmark.

Abstract

A hydroxyapatite-coated hip hemi-prosthesis was retrieved from a 98-year-old osteoporotic woman 12 weeks after implantation. Histologic analysis revealed bone and fibrous tissue almost evenly distributed around the surface of the implant circumference. Quantitative histologic analysis showed that 48% of the hydroxyapatite surface was covered by bone. Fibrous tissue covered 30% of the prosthetic surface, and 20% of the surface had no tissue coverage. Scanning electron microscopy showed direct contact without any clear boundary between the newly formed bone and the hydroxyapatite ceramic.

PMID:: 1657474; [PubMed - indexed for MEDLINE]

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