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Voriconazole therapeutic drug monitoring.
University of Wisconsin, Department of Medicine, Madison, WI 53792, USA.
We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.
PMID: 16569888 [PubMed - indexed for MEDLINE]
PMCID: PMC1426935
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Cited by 11 PubMed Central articles
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Fatal disseminated Trichosporon asahii infection in a child with acute lymphoblastic leukemia.
Thibeault R, Champagne M, de Repentigny L, Fournet JC, Tapiero B, Moghrabi A, Ovetchkine P.
Can J Infect Dis Med Microbiol. 2008 Mar; 19(2):203-5.
[Can J Infect Dis Med Microbiol. 2008]
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ReviewAntifungal therapeutic drug monitoring: established and emerging indications.
Andes D, Pascual A, Marchetti O.
Antimicrob Agents Chemother. 2009 Jan; 53(1):24-34. Epub 2008 Oct 27.
[Antimicrob Agents Chemother. 2009]
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Inhibition of voriconazole metabolism by chloramphenicol in an adolescent with central nervous system aspergillosis.
Hafner V, Albermann N, Haefeli WE, Ebinger F.
Antimicrob Agents Chemother. 2008 Nov; 52(11):4172-4. Epub 2008 Sep 15.
[Antimicrob Agents Chemother. 2008]
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