Antimicrob Agents Chemother. 2006 Apr;50(4):1570-2.

Voriconazole therapeutic drug monitoring.

Smith J, Safdar N, Knasinski V, Simmons W, Bhavnani SM, Ambrose PG, Andes D.

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University of Wisconsin, Department of Medicine, Madison, WI 53792, USA.

Abstract

We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.

PMID:: 16569888; [PubMed - indexed for MEDLINE]
PMCID: PMC1426935

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Cited by 25 PubMed Central articles

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