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Analyst. 2006 Apr;131(4):568-72. Epub 2006 Feb 21.

Surface-enhanced Raman spectroscopy of half-mustard agent.

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  • 1Department of Chemistry, Northwestern University, 2145 Sheridan Rd Evanston, IL 60208-3113, USA.


The detection and identification of chemical warfare agents is an important analytical goal. Herein, it is demonstrated that 2-chloroethyl ethyl sulfide (half-mustard, CEES) can be successfully analysed using surface-enhanced Raman spectroscopy (SERS). A critical component in this detection system is the fabrication of a robust, yet highly enhancing, sensor surface. Recent advances in substrate fabrication and in the fundamental understanding of the SERS phenomenon enable the development of improved substrates for practical SERS applications.

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