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Clin Lab Med. 2006 Mar;26(1):67-97, viii.

Heavy metal poisoning: clinical presentations and pathophysiology.

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  • 1Department of Emergency Medicine, Division of Medical Toxicology, Indiana University School of Medicine, 1050 Wishard Boulevard, Room 2200, Indianapolis, IN 46202, USA.


Humans have had a long and tumultuous relationship with heavy metals. Their ubiquitous nature and our reliance on them for manufacturing have resulted at times in exposures sufficient to cause systemic toxicity. Their easy acquisition and potent toxicity have also made them popular choices for criminal poisonings. This article examines the clinical manifestation and pathophysiology of poisoning from lead, mercury, arsenic, and thallium.

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