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Nat Biotechnol. 2006 Apr;24(4):435-6. Epub 2006 Mar 26.

Generation of cloned transgenic pigs rich in omega-3 fatty acids.

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  • 1Division of Animal Science, University of Missouri-Columbia, Columbia, Missouri 65211, USA.

Abstract

Meat products are generally low in omega-3 (n-3) fatty acids, which are beneficial to human health. We describe the generation of cloned pigs that express a humanized Caenorhabditis elegans gene, fat-1, encoding an n-3 fatty acid desaturase. The hfat-1 transgenic pigs produce high levels of n-3 fatty acids from n-6 analogs, and their tissues have a significantly reduced ratio of n-6/n-3 fatty acids (P < 0.001).

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PMID:
16565727
[PubMed - indexed for MEDLINE]
PMCID:
PMC2976610
Free PMC Article

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