Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Future Oncol. 2005 Apr;1(2):205-7.

The potential of targeting malignant stem cells as a treatment for leukemia.

Author information

  • University of Rochester School of Medicine, 601 Elmwood Ave, Box 703 Rochester, NY 14642, USA. craig_jordan@urmc.rochester.edu

Abstract

Malignant stem cells have recently been described as the source of several types of human cancer. These unique cell types are typically rare and possess properties that are distinct from most other tumor cells. In leukemia, the natural properties of cancer stem cells indicate that current chemotherapy drugs will not be effective. Consequently, new strategies are required that specifically and preferentially target the cancer stem cell population, whilst sparing normal stem cells. This perspective article summarizes recent findings in the leukemia stem cell field and discusses new directions for therapy.

PMID:
16555992
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Atypon
    Loading ...
    Write to the Help Desk