J Clin Epidemiol. 2006 Apr;59(4):336-8; discussion 339-41.

Unsubstantiated claims of large effects of placebo on pain: serious errors in meta-analysis of placebo analgesia mechanism studies.

Hróbjartsson A, Gøtzsche PC.

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The Nordic Cochrane Centre, Rigshospitalet, Denmark. ah@cochrane.dk

Comment on

The nature and power of the placebo effect. [J Clin Epidemiol. 2006]
The nature and power of the placebo effect.Miller FG, Rosenstein DL. J Clin Epidemiol. 2006 Apr; 59(4):331-5.

PMID:: 16549252; [PubMed - indexed for MEDLINE]

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Factors contributing to large analgesic effects in placebo mechanism studies conducted between 2002 and 2007. [Pain. 2009]
Factors contributing to large analgesic effects in placebo mechanism studies conducted between 2002 and 2007.
Vase L, Petersen GL, Riley JL 3rd, Price DD. Pain. 2009 Sep; 145(1-2):36-44. Epub 2009 Jun 25.
Trial methodology and patient characteristics did not influence the size of placebo effects on pain. [J Clin Epidemiol. 2008]
Trial methodology and patient characteristics did not influence the size of placebo effects on pain.
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Review A continuum for using placebo interventions in regional anesthesia and analgesia studies.
Waisel DB, Truog RD. Clin Pharmacol Ther. 2008 Jul; 84(1):163-5. Epub 2008 May 7.
Is the placebo powerless? [N Engl J Med. 2001]
Is the placebo powerless?
Spiegel D, Kraemer H, Carlson RW. N Engl J Med. 2001 Oct 25; 345(17):1276; author reply 1278-9.
Review The nature and power of the placebo effect. [J Clin Epidemiol. 2006]
Review The nature and power of the placebo effect.
Miller FG, Rosenstein DL. J Clin Epidemiol. 2006 Apr; 59(4):331-5.

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Cited by 2 PubMed Central articles

Review Biological, clinical, and ethical advances of placebo effects. [Lancet. 2010]
Review Biological, clinical, and ethical advances of placebo effects.
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Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesia. [Neuroimage. 2007]
Functional brain interactions that serve cognitive-affective processing during pain and placebo analgesia.
Craggs JG, Price DD, Verne GN, Perlstein WM, Robinson MM. Neuroimage. 2007 Dec; 38(4):720-9. Epub 2007 Aug 16.

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Unsubstantiated claims of large effects of placebo on pain: serious errors in me...
Unsubstantiated claims of large effects of placebo on pain: serious errors in meta-analysis of placebo analgesia mechanism studies.
J Clin Epidemiol. 2006 Apr ;59(4):336-8; discussion 339-41.

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